Switchable Site-Selective Catalytic Carboxylation of Allylic Alcohols with CO2

A switchable site-selective catalytic carboxylation of allylic alcohols has been developed in which CO₂ is used with dual roles, both facilitating C−OH cleavage and as a C₁ source. This protocol is characterized by its mild reaction conditions, absence of stoichiometric amounts of organometallic reagents, broad scope, and exquisite regiodivergency which can be modulated by the type of ligand employed.     

New phosphorylating reagents for deoxyribonucleosides and oligonucleotides

New phosphorylating reagents 1 and 2 were prepared in three steps from 4-hydroxybenzaldehyde. They showed good efficiency in the solid phase synthesis of 5′-phosphate monoester nucleosides. End-phosphate DNA sequence synthesis demonstrated the efficiency of the new reagents (1 and 2) according to the general procedure of automated DNA synthesis. The oxidation of P(III) to P(V) and the removal of benzyl protecting groups were achieved in a single step by treatment with a 0.02 M I₂/pyridine/H₂O solution. Due to this one-pot treatment, it is possible to use the phosphorylating reagents (1 and 2) for the synthesis of base-sensitive ODNs. The reagents 1 and 2 are unique among phosphorylating reagents.     

Participating life insurance policies: an accurate and efficient parallel software for COTS clusters

In this paper we discuss the development of a parallel software for the numerical simulation of Participating Life Insurance Policies in distributed environments. The main computational kernels in the mathematical models for the solution of the problem are multidimensional integrals and stochastic differential equations. The former is solved by means of Monte Carlo method combined with the Antithetic Variates variance reduction technique, while differential equations are approximated via a fully implicit, positivity-preserving, Euler method. The parallelization strategy we adopted relies on the parallelization of Monte Carlo algorithm. We implemented and tested the software on a PC Linux cluster.     

Magnetic and quasiparticle excitation spectra of an itinerant J1-J2 model for iron-pnictide superconductors

We calculate the magnetic and quasiparticle excitation spectra of an itinerant J(1)-J(2) model for iron-pnictide superconductors. In addition to an acoustic spin-wave branch, the magnetic spectrum has a second, optical branch, resulting from the coupled four-sublattice magnetic structure. The spin-wave velocity has also a planar directional anisotropy, due to the collinear or striped antiferromagnetism. Within the magnetically ordered phase, the quasiparticle spectrum is composed of two Dirac cones, resulting from the folding of the magnetic Brillouin zone. We discuss the relevance of our findings to the understanding of both neutron scattering and photoemission spectroscopy results for SrFe(2)As(2).     

Star-regularity and regular completions

In this paper we establish a new characterisation of star-regular categories, using a property of internal reflexive graphs, which is suggested by a recent result due to O. Ngaha Ngaha and the first author. We show that this property is, in a suitable sense, invariant under regular completion of a category in the sense of A. Carboni and E.M. Vitale. Restricting to pointed categories, where star-regularity becomes normality in the sense of the second author, this reveals an unusual behaviour of the exactness property of normality (i.e. the property that regular epimorphisms are normal epimorphisms) compared to other closely related exactness properties studied in categorical algebra.     

Relative symplectic subquadrangle hemisystems of the Hermitian surface

We introduce the notion of relative subquadrangle regular system of a generalized quadrangle. A relative subquadrangle regular system of order m on a generalized quadrangle S of order (s, t) is a set \({\mathcal R}\) of embedded subquadrangles with a prescribed intersection property with respect to a given subquadrangle T such that every point of S T lies on exactly m subquadrangles of \({\mathcal R}\) . If m is one half of the total number of such subquadrangles on a point we call \({\mathcal R}\) a relative subquadrangle hemisystem with respect to T. We construct two infinite families of symplectic relative subquadrangle hemisystems of the Hermitian surface \({{\mathcal H}(3,q^2)}\) , q even.     

Existence, multiplicity and concentration of bound states for a quasilinear elliptic field equation

In this paper we study existence, multiplicity and concentration of solutions for the following nonlinear field equation where the potential V is positive and W is an appropriate singular function. Here is regarded as a small parameter. Under suitable conditions on V and W we find solutions exhibiting a concentration behaviour at an absolute minimum of V as Such solutions are obtained as local minima for the associated functional; the proofs of our results rely on a careful analysis of the behaviour of minimizing sequences and use arguments inspired by the concentration-compactness principle. Received July 21, 1999; Accepted April 9, 2000 / Published online September 14, 2000     

Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Four new jaspamide derivatives with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analysis. A structure-activity relationship analysis on all natural jaspamides is also reported here.     

Fast multidimensional localized parallel NMR spectroscopy for the analysis of samples

A parallel localized spectroscopy (PALSY) method is presented to speed up the acquisition of multidimensional NMR (nD) spectra. The sample is virtually divided into a discrete number of nonoverlapping slices that relax independently during consecutive scans of the experiment, affording a substantial reduction in the interscan relaxation delay and the total experiment time. PALSY was tested for the acquisition of three experiments 2D COSY, 2D DQF‐COSY and 2D TQF‐COSY in parallel, affording a time‐saving factor of 3–4. Some unique advantages are that the achievable resolution in any dimension is not compromised in any way: it uses conventional NMR data processing, it is not prone to generate spectral artifacts, and once calibrated, it can be used routinely with these and other combinations of NMR spectra. Copyright © 2010 John Wiley & Sons, Ltd.